Maurice Wilkins, a scientist working at King´s College London, collected X-ray diffraction patterns of DNA in 1950. In 1944 Oswald Avery, Colin MacLeod and Maclyn McCarty published an experiment that isolated DNA as the material that contained genes. However, at that time scientists generally agreed that DNA merely provided structural support for cells and that protein must be genetic material. At the time of Astbury´s experiments, scientists had determined the chemical composition of DNA. However, Astbury´’s diffraction patterns were blurry and difficult to interpret. William Thomas Astbury, a crystallographer working at the University of Leeds in Leeds, England, gathered the first diffraction patterns of DNA in 1937. Scientists began collecting X-ray diffraction patterns of DNA in the 1930s before they confirmed that DNA contained genes. The pattern of dark marks on the film gives scientists information about the structure of the crystal. When the X-rays scatter, they strike a film mounted behind the crystal and leave a pattern of dark marks. When X-rays interact with electrons in a crystal the X-rays scatter, or diffract, at angles that indicate the arrangement of atoms in the crystal, or its structure. Because of their short wavelength, X-rays can pass through a crystal and interact with the electrons of the atoms within the crystal. X-rays are electromagnetic waves that have a shorter wavelength and higher energy than visible light. ![]() The X-ray tube generates X-rays that strike the purified material. ![]() To perform an X-ray crystallography, scientists mount a purified fiber or crystal in an X-ray tube. Photo 51 used DNA fibers, DNA crystals first produced in the 1970s. Some biological macromolecules, such as DNA, can form fibers suitable for analysis using X-ray crystallography because their solid forms consist of atoms arranged in a regular pattern. Crystals are solids with regular, repeating units of atoms. X-ray crystallography, the technique Franklin used to produce Photo 51 of DNA, is a method scientists use to determine the three-dimensional structure of a crystal. ![]() Franklin´s Photo 51 helped scientists learn more about the three-dimensional structure of DNA and enabled scientists to understand DNA´s role in heredity. In 1962, after Franklin´s death, Watson, Crick, and Wilkins shared the Nobel Prize in Physiology or Medicine for their findings about DNA. Watson and Crick used that image to develop their structural model of DNA. Maurice Wilkins, Franklin´s colleague showed James Watson and Francis Crick Photo 51 without Franklin´s knowledge. Franklin took Photo 51 after scientists confirmed that DNA contained genes. Photograph 51, or Photo 51, revealed information about DNA´s three-dimensional structure by displaying the way a beam of X-rays scattered off a pure fiber of DNA. On, at King´s College London in London, England, Rosalind Franklin photographed her fifty-first X-ray diffraction pattern of deoxyribosenucleic acid, or DNA. Photograph 51, by Rosalind Franklin (1952)
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Laila is a sophomore at the New Paltz High School. Last August she dropped an EP, and a month later, a single. Laila Mach – Teen singer from Poughkeepsie, New York has over 30K subscribers on her Youtube channel and has just released an album called Stuck on You.In 2015 the video for “Got This Feeling” premiered on Tiger Beat and Us Magazine. She put out a full length record My Metropolis on Gladiator. She and her father wrote “Crazy Glue” which season 11 runner-up Jessica Sanchez covered on her 2011 EP. Simon Cowell signed the Toronto singer to his Syco Records at the age of 10. Heather Russell – Heather is only 20, but she’s been in the music business for 10 years.The young singer graduated from USC last year. She got on the soundtrack by submitting an audition tape. The Malaysian singer-songwriter appeared on the Crazy Rich Asians soundtrack, contributing the opening/closing track “ Money (That’s What I Want)” in both English and Mandarin Chinese. Cheryl K – Cheryl is already kinda famous.She cheered in school, and also competed in beauty and talent pageants growing up. The Chilton, Alabama singer has been watching Idol all of her life. Cameron McGhar – Cameron sang “Girl Crush” by Little Big Town in front of the judges.Instagram Live at Smileys Watch Caleb sing “Nowhere” for the judges HERE. In this piece, the reporter describes Caleb singing original tunes “That’s My Papa” (written for his grandfather) and “Nowhere” for a hometown crowd in Spartanburg, SC. He flew for the first time, to California. Caleb Kennedy – Sixteen year old high school student performed “Can’t You See” by the Marshall Tucker Band and “When it Rains it Pours” by Luke Combs for producers.In the meantime, the singer has released original music. The pandemic drove him to audition for Idol. ![]() In Boston, free to be himself, he came out as gay. After high school, he got accepted to Berklee College of Music, graduating in 2019. He’s been studying music since age 5, and participated in school musicals. Beane – Twenty-three year old singer from Montoursville, PA.The song “chronicles his two decade struggle with addiction.” She auditioned for The Voice, but “didn’t make the cut.” Here’s a recent tune called “Mine.” Instagram Youtube ![]() According to the Modesto Bee, Ash will sing an original song “Bryan’s Song” and dedicate it to her father.
![]() For twelve years before (1821), when Pike County was first carved out of Illinois territory, the county seat was southwest of Hardin at Coles Grove for two years. ![]() Pittsfield was created to be the county seat in 1833. To explain this situation, look to early history of the area. It is the third courthouse in the town, but the fourth in the county. Pittsfield is not the first county seat of Pike County, nor is the red-domed courthouse the first in Pittsfield. In this building the county business is conducted trials held taxes paid births deaths, marriages recorded traffic tickets paid passport applications made dog licenses received records of land acquisitions and sales made and assistance for the poor given. The red-domes structure sits like a huge crown on the square block of green grass in the center of Pittsfield, the county seat of Pike County. Local Superintendent of construction H.J.Total cost of building and fixtures – $ 68,520.28.Cost of architects and Building Committee – $ 4,465.52.Cost of wood furniture, office furniture, and light fixtures – $ 7,482.40.Robert Franklin, Nebo, was the designer of keystone architecture.Architect Washburn designed the oak furniture in the courthouse.Ceiling over rotunda is of stained cathedral glass.Built of Cleveland sandstone veneering back by walls of brick.Courthouse is octagonal shaped outside, Cruciform inside. A higher turnover rate implies a more active management approach, where the fund’s holdings are frequently adjusted based on market conditions and investment strategies. It provides investors with insights into the level of engagement and decision-making of the fund manager. Turnover rate serves as a measure of the fund’s trading activity and reflects how frequently the fund’s portfolio is being bought and sold. To calculate the turnover rate, we divide the total value of transactions ($100 million + $80 million = $180 million) by the average NAV ($500 million). The average net asset value (NAV) of the fund is $500 million. Suppose a mutual fund has total buy transactions of $100 million and sell transactions of $80 million during a year. To illustrate, let’s consider an example. The turnover rate is typically expressed as a percentage and is calculated by dividing the total value of securities bought or sold (whichever is higher) by the average net asset value (NAV) of the fund. It is a measure of the level of trading activity within the fund. Turnover rate in the context of mutual funds refers to the ratio of securities bought and sold within a particular time period. By the end, you will have a clear understanding of the importance of turnover rate in assessing the potential risks and rewards of investing in mutual funds. Additionally, we will discuss strategies that fund managers employ to manage turnover effectively. We will also explore how turnover rate is calculated, factors that influence it, and the implications of a high turnover rate on mutual fund performance. In this article, we will delve into the definition of turnover rate and its significance in the realm of mutual funds. The turnover rate is an essential indicator for investors to understand as it impacts the overall performance, costs, and tax implications of investing in a mutual fund. A higher turnover rate suggests that the fund’s holdings are being traded frequently, whereas a lower turnover rate implies a more passive approach to managing the portfolio. The turnover rate acts as a window into how actively the fund’s management team is trading the underlying assets. It is expressed as a percentage and signifies the level of activity within the fund. The turnover rate of a mutual fund is a metric that measures the frequency at which the fund’s portfolio holdings are bought and sold within a specific period. ![]() ![]() When evaluating the performance of a mutual fund, one crucial factor to consider is its turnover rate. In the world of finance, mutual funds are a popular investment option for individuals looking to diversify their portfolios and potentially earn attractive returns. Impact of Turnover Rate on Mutual Fund Performance.Importance of Turnover Rate in Mutual Funds. ![]() So two people from my company lost two hours, during crunch time, and we had to scramble to get a van from another company. There were no other vans available in our area. Customer service was lovely, but unable to help. Started the check out process, and noticed damage, including a flat tire. We drove out to a lot to get a cargo van. ![]() Then, in desperation, we tried Fluid again. We were quiet, and we never heard from him again. This story gets worse, but eventually a sales manager offered to make good on our loses if we kept this quiet. We called Fluid to check with them about their van tracking, before we called the police to report the theft. Despite Fluid having all of the information about the correct van still being on the lot, and who had been at the lot when the other van was taken (which should not have been possible), Fluid repossessed the van from the street (in front of our billing address), with thousands of dollars of our equipment and rental items in it. On one occasion, my people had issues with the app, and took the wrong van (which should not have been possible). On more than one occasion, the van we rented was dangerously unreliable or damaged. On more than one occasion, the van we rented was completely out go fuel. Only to have them circling some remote area, and finding nothing. We have sent people out into the night, driving 30-45 minutes to get a van. On more than one occasion, we have booked a van at a location that does not seem to exist, to the van own question is not there. My business requires we rental cargo vans, sometimes with little notice, and Fluid seemed like it was THE solution we were looking for. Fluid buys cargo vans that have really been through it, and allows it customers to take a chance on their continued use, but for a low price, Fluid has a good enough app, that allows their customers to find an available van 24/7, and check out that van as needed. Let's go over the good before I tell you why you should never do business with this company. ![]() My RL identity has nothing to do with any celebrity or anyone like that. I am User:Wifione, the admin who got blocked years ago. In response, Lourdes gave an admission nobody expected: This kind of pressuring (there were other examples) was described by one of the contributors to the case request as "the kind of thinly veiled threat you'd expect to hear in The Godfather". The arbitration case request filed this month alleged that Lourdes engaged in egregious abuse of their administrator status during a recent request for adminship, including the following:īecause I remember having acted on your complaints at ANI a few times, and on the basis of that connect and support that I gave you, I am requesting you to reconsider your stand Throughout their tenure, they made 2,282 admin actions, according to User:JamesR/AdminStats. In 2023, they returned to regularly editing the English Wikipedia. The account went mostly unused for 2020 through 2022, with many months of total editorial inactivity, although it continued to perform admin actions. They were most active in 2016–17, and ran an unsuccessful, self-nominated request for adminship in early 2017 a second attempt in 2018 was successful with 207 in favor and 3 opposed. This long-term abuser created the Lourdes account in late 2015, initially under a different name. Wifione was sitebanned as part of the case resolution. ![]() The Arbitration committee case found that Wifione was engaging in search engine optimization related to an Indian educational firm. That prior account was later linked to another account called Wifione, which was created in 2009 and that had become a Wikipedia admin in 2010. They created dozens of sock accounts, which were revealed by a 2008 checkuser request. If you have read our prior coverage of how the Wifione siteban came to be, amidst allegations of paid editing while holding the admin bit, you can probably skip over this section.Īccording to the 2015 Arbcom case, the oldest known account used by the individual also known as Wifione was created in 2006. Night Shyamalan movie?" Others, like arbitrator Moneytrees in the quote above, were more to-the-point. One of the contributors to the case, Kurtis, asked "Is this an ArbCom case request or an M. The case request was closed as moot following Lourdes' admission. With the case request around one day old, on 2 November, the respondent suddenly stated that they are the site-banned former admin Wifione. November 1 case request and startling admissionīeeblebrox opened a request for arbitration against administrator Lourdes on 1 November, claiming misdeeds including administrative blackmail - bullying other less-privileged editors over their votes during a recent request for adminship. We are sad to report that, not only did the abuse not stop in 2015, but the same person managed to obtain a second administrator account, and was just discovered a few days ago. At that time, they were banned by the Arbitration Committee following a long case. arbitrator Moneytrees, arbitration request for LourdesĪ 2015 arbitration report in this very periodical said "it was a matter of deep concern" that an abusive editor who had obtained administrator privileges "was able to fool the community for so long". The taste, texture, and nostalgia of a spoonful of cookie dough is hard to beat - just ask TikTok, where RDNs and food bloggers alike have racked up millions of views on videos tagged #cookie dough (1.7B views) and #ediblecookiedough (287.7M views). ![]() There you go.While a freshly-baked cookie warm out of the oven is a classic dessert, cookie dough itself has become a treat of its own. Swap the all purpose flour for a mix of gluten free oat flour and coconut flour to make it gluten free.Swap the maple syrup for equal amounts of brown sugar, or slightly less honey (again, not vegan) or agave.Swap the coconut oil for vegetable oil or melted butter (not vegan).Microwave the dough for 15 seconds for gooey melted chocolate cookie dough.For a baked version, try this vegan chocolate chip cookie for one or these vegan oatmeal chocolate chip cookies.If you want vegan peanut butter single serving cookie dough try this version.People have already shared tons of adaptations in the comments, but here are a few of the highlights: See the customization options below for baked options. While this tastes delicious as raw dough, it lacks some of the necessary ingredients to turn it into an actual cookie. You can read my post on how to make edible cookie dough for a full breakdown on what makes this edible cookie dough safe to eat. You’ll need to skip the eggs and heat your flour to remove any bacteria. How do you make cookie dough safe to eat? To make your flour safe to eat, toast the flour on a baking sheet in a 350✯ oven for 5 minutes before using. It is generally considered unsafe to eat raw flour. Recently there have been concerns about eating raw flour. If you measure carefully it shouldn’t taste too much like coconut or maple, although you might still taste it a tiny bit. Does this vegan cookie dough taste like maple syrup?Ĭoconut oil and maple syrup are strong flavors, but I find they cancel each other out in this recipe. If you’d like to learn more about the health benefits of coconut oil I recommend reading The Coconut Oil Miracle by Bruce Fife. If it comes out too runny for you just pop it in the fridge for a few minutes and it’ll firm right up. My house is pretty cold in this polar vortex, so after some good ol’ stirring it was perfect for me. The temperature of the oil makes a big difference on the consistency here. It melts in your mouth and doesn’t taste too terribly coconut-y. Top questions Coconut oil in cookie dough?Ĭoconut oil (affiliate link) is magic. Mix the melted coconut oil with the maple syrup and vanilla extract.With only six ingredients, you might already have everything you need on hand. ![]() This is the healthiest, easiest cookie dough you’ll ever throw together in a moment of need. Vegan cookie dough! And you’re not sharing – we’re talking edible cookie dough for one. Sometimes you’re pregnant (I’m not) and you really just shouldn’t be eating raw eggs or flour. ![]() Sometimes you just want a treat without having to mix up a whole batch of cookies. Sometimes you just want edible cookie dough. And then you eat the cookies that just came out of the oven. You know it’s a little bit dangerous (raw eggs! raw flour!!) but one bite isn’t gonna kill you, right? And do you really know anyone who has ever gotten sick from eating cookie dough? But ultimately, you’re there for the dough. ![]() Manual mode allows you to tweak Sharpness, Suppress Noise and Add Grain to your heart’s content. You can also choose between Manual and Auto mode, with the latter choosing image specific settings based on the software’s artificial intelligence detection. (If you want to learn more about each of the 3 options above, I recommend you look here at the product page, which gives some great example before/afters explaining each concept.) It’s good to play around with each of the settings since often, it’s not clear which one best applies to the photo you shot. Under that, you can choose between 3 different AI Correction Models to enhance your image: The right side is home to all of your control options: un-toggling the ‘Auto-update preview’ reveals an Update button. Masking is a simple and effective way of limiting the effects of the chosen tool. the bokeh areas), and masking helped control this. I found the Masking feature most useful when trying to control depth of field adjustments in the photo – sometimes AI Sharpen would add sharpening to areas which should remain out of focus (i.e. When you toggle the Masking button, another option panel appears, allowing you to select further features such as using Edge-aware or an Overlay. There’s a useful option to paint a ‘Mask’ on to your image, effectively telling the software what to ignore when making its processing adjustments. You can also the Navigator to drag the image.) (A small niggle is that the mouse cursor only ‘drags’ the image on the ‘Original’ side of the Side-by-Side view. ![]() Changing views requires the preview to regenerate. In order to compare the Before/After versions of your image, you can choose Single View, Split View or Side-by-Side view. One tip to make things run a bit faster is to turn off ‘Auto-update preview’: The main portion of the screen shows a zoomed portion of your photo with the default sharpening and noise suppression already applied.Įach time you drag to move the placement of the zoomed area, the software needs to generate the preview again, which can take a few seconds. All subsequent adjustments will also take more time. If you’re loading a RAW file (or an enormous JPEG), the software will take a few seconds to render the image. You don’t even need to install the plugin – it just appears in your Lightroom menu automatically. If you’re an Adobe Lightroom Classic user like me, you can open your image using the Photo > Edit In menu option, which launches the Sharpen AI interface with your chosen photo pre-optimised.įor those of us ingrained in Lightroom or Photoshop image editing workflows, the Sharpen AI plugin keeps file movements simple and efficient. ![]() In the middle of the screen is an Open icon, which allows you to start importing either single or multiple images – thankfully the tool supports batch processing. There are also plenty of support videos and tutorials on the Topaz website, and a lively user forum too. When launching the software for the first time, you’re greeted with a four-slide user guide. The interface is uncluttered and simple to navigate.Īs with all Topaz Labs products, the Sharpen AI interface is very minimal, making it simple to understand and use. You can also get Topaz Sharpen as part of the new Topaz Photo AI editing software. NVIDIA: Minimum requirement of 2GB of dedicated VRAM (GT 740 or greater) A recommended requirement of 4GB of dedicated VRAM (GTX 970 or greater) An optimal requirement of 8GB of dedicated VRAM (GTX 1080 or greater).Ryzen 7 or greater (4GHz and above) is recommended. AMD: Ryzen 5 or equivalent (3.0GHz and above).Intel i7 or greater (4GHz and above) is recommended. Intel: i5 or equivalent (3.0GHz and above).Graphics Drivers and OpenGL version 3.3 or later.Hard disk space: 4 GB pr more recommended.RAM: 8 GB of RAM (16 GB recommended, 32 GB Optimal).Operating system: Windows 7, 8, 10 (64-bit only) macOS version 10.12 (Sierra) and above. ![]() Processor: Intel multi-core or better, Xeon or AMD equivalent.The Utility Bundle is currently on discount, and great value for money for photographers wishing to save time fixing and enhancing their images. Topaz offer a range of photo editing tools which can be bought separately, or as part of a Utility bundle, which includes Sharpen AI, as well as DeNoise AI, Gigapixel AI and JPEG to RAW AI. It’s available as a standalone app or a plugin for Adobe Photoshop, Lightroom or Topaz Studio. Topaz Sharpen AI is a sharpening and shake reduction photo retouching software, which can help make blurry or out-of-focus areas of your photos sharper. ![]() He plays BOTH Pan (the faun creature) and The Pale Man. In the film he wants to be remembered for, Doug portrays 2 characters in the Oscar winning film PAN’S LABYRINTH (in the native tongue of Spanish “El Laberinto del Fauno”). He’s also the life and soul of ABE SAPIEN in HELLBOY and HELLBOY II THE GOLDEN ARMY (based on the popular Dark Horse comic book, returning to his role of ABE SAPIEN as well a taking on 2 other roles, that of THE CHAMBERLAIN and THE ANGEL OF DEATH for director Guillermo del Toro.)! Saru in CBS’ “Star Trek Discovery (perhaps one of the best “Trek” series to hit airways)! He can also be seen in the Academy Award winning film “The Shape of Water” in which Doug teams up again to bring an original story to life by director Guillermo del Toro!įans will long remember Doug for his work as THE SILVER SURFER in FANTASTIC FOUR RISE OF THE SILVER SURFER. Some say he is this generations “Boris Karloff”!ĭoug’s career spans numerous years in television and on film, currently Doug can be seen as Lt. Jason Isaacs as Captain Lorca, Doug Jones as science officer Saru, Anthony Rapp as fellow science officer Stamets, Terry Serpico as Starfleet admiral Anderson, Maulik Pancholy as chief medical officer Nambue, Sam Vartholomeos as junior Starfleet officer Connor, Mary Wiseman as Cadet Tilly, James Frain as Sarek, astrophysicist and father of Spock, Chris Obi as Klingon leader T’Kuvma, Mary Chieffo as L’Rell, a Klingon commander, Shazad Latif as Lieutenant Tyler, Rekha Sharma as Commander Landry, Kenneth Mitchell as Kol, Clare McConnell as Dennas, Damon Runyan as Ujilli, and Rainn Wilson as Harry Mudd.Doug Jones is perhaps one of the most brilliant actors of our time. The series also stars Michelle Yeoh as Captain Philippa Georgiou. You can bet they'll be showing off new footage from the series and revealing more details about the story and the characters.ĭiscovery stars Sonequa Martin-Green ( The Walking Dead) as a brilliant Starfleet First Officer - the first human educated on Vulcan - who’s forced to make an impossibly difficult decision which impacts the entire Federation. Jones and the rest of the Discovery cast will be attending the Star Trek: Discovery Comic-Con panel, which will take place Saturday, July 22 at 2:30 p.m. ![]() I have no doubt that Jones is going to own the role! Sounds like a cool character that fans can look forward to getting to know better over the course of the series. Saru is all of those things and then some.” On Falling Skies, I played an alien species who came to Earth to help the humans fight back the bad aliens who’d taken over, and I was intelligent, well-spoken, had a lot of answers and science-y smart. Hey! Every Star Trek series needs one! He also compares his Star Trek character to the alien character he played on Falling Skies: “ said Saru is the Spock of the series, he’s the Data of the series - and those are beloved characters that I always connect with whenever I would watch the past incarnations of Star Trek. Saru is the Spock and Data of the series. Jones offers his thoughts on the character he plays and says that Lt. That's actually kind of a cool backstory for the character. Such prey species tend to have a cowardly reputation in the Federation, but Saru should not be underestimated. As part of the latter group, Saru has evolved with heightened survival instincts. The report goes on to offer us a little background on the character and where he comes from: On Saru’s planet, there’s a dominant predator species that constantly imperils another weaker species called Kelpiens. We managed to get a little tease of the character in the trailer that was released and according to showrunner Aaron Harberts, he has the power of sensing death! That's got to be one of the most depressing powers ever! “What we can tell you that adds the context to that clip where he says he can sense the coming of death is that he comes from a planet where he’s a ‘prey species.’ He’s the first of his kind to make it to Starfleet.” He's described as being the "Spock" of the series. Saru and he is the Starfleet Science Officer. What we have known is that Jones plays a character named Lt. ![]() ![]() Until now, we really didn't know much about who he's playing, but thanks to EW, we have some intriguing new information to share with you. As a fan of Doug Jones, one of the things I'm looking forward to most about Star Trek: Discovery is seeing him play this new alien character. ![]() ![]() SyncMate gives you great power to sync your Mac data. 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Flexible Mac file sync utility to suit your needs. GoodSync for Mac is a free download, and comes with a 30-day trial. ![]() Download SyncMate Expert 8.3 for Mac full version complete standalone offline program setup free for macOS Big Sur. SyncMate is the only Mac file synchronizer you need to sync files between your computer and devices. |
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